SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
USERS' SCORE
Good
Based on 28 Reviews
8.2
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**

Top Medical Research Studies

9
Methylcobalamin protects against liver failure
Methylcobalamin protects against liver failure via engaging gasdermin E.
High relevance to liver treatment
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.

In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
Read More
7
Vitamin B6 may protect liver health
The gut microbiota-produced vitamin B6 mitigates alcohol-associated liver disease by attenuating hepatic oxidative stress damage.
Moderately relevant to liver health
We investigated the connection between vitamin B6 and alcohol-associated liver disease (ALD) using a mouse model. Through a detailed analysis of the gut microbiota, we observed that disruptions significantly lowered vitamin B6 production. This reduction heightened oxidative stress and worsened liver damage. Our results indicate that maintaining vitamin B6 levels could be vital in protecting against ALD progression by influencing important metabolic processes. Despite some promising findings, the protective effects of vitamin B6 against ALD warrant further exploration before drawing definitive conclusions.
Read More
7
Vitamin B and Folate Related to Mortality
Associations of serum folate and vitamin B levels with all-cause mortality among patients with metabolic dysfunction associated steatotic liver disease: a prospective cohort study.
High relevance to liver disease research
We explored how serum folate and vitamin B levels relate to all-cause mortality among individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). Utilizing data from the Third National Health and Nutrition Examination Survey, we followed nearly 3,636 MASLD subjects for over 20 years.

Our findings indicated that lower levels of these vitamins were tied to a higher risk of mortality. Specifically, individuals with serum vitamin B and folate levels above the median experienced significant reductions in mortality risk, underscoring the potential importance of these nutrients for liver health.
Read More

Most Useful Reviews

9
Normalises liver function
I drink with my husband 2 course, excellent composition, well absorbed, works great. It helps to normalise liver function and improves sleep. Affects the nervous system positively, reduces anxiety and relieves stress. I noticed it improves my overall well-being. Don't fear high dosages as these are water-soluble vitamins; the body only takes what it needs, and the excess is excreted.
Read More
9.5
Normalises liver function
Perfectly absorbed, these vitamins support the nervous system and help normalise liver function. There’s no need to worry about large dosages, as they are water-soluble, meaning the body uses what it requires and excretes the rest. They also improve sleep, reduce anxiety, relieve stress, and alleviate muscle weakness.
Read More
9.5
Supports overall energy
This super complex of bioavailable B vitamins is excellent! Although urine may turn yellow, it indicates the supplement's effectiveness. As they are water-soluble, there’s no risk of overdose. Taking two daily supports the nervous system, liver, and overall energy.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.8
  • All Researches
9
Methylcobalamin protects against liver failure
Methylcobalamin protects against liver failure via engaging gasdermin E.
High relevance to liver treatment
We investigated how methylcobalamin, a form of vitamin B12, affects liver failure, particularly in cases of cholestasis. Methylcobalamin showed promise as it directly binds to and inhibits Gasdermin E, a protein linked to liver cell death.

In mouse models, this vitamin significantly reduced liver inflammation and damage, lowering mortality rates. These findings suggest that methylcobalamin could be a potential treatment option for preventing severe liver failure and related health issues.
Read More
8
Antioxidants may protect liver health
Effects of adenosine triphosphate, thiamine pyrophosphate, melatonin, and liv-52 on subacute pyrazinamide proliferation hepatotoxicity in rats.
High relevance to liver therapy
We explored the impact of four potential protective agents—ATP, thiamine pyrophosphate, melatonin, and Liv-52—against liver damage caused by the antibiotic pyrazinamide in a rat model.

In a carefully designed study with 36 rats split into various treatment groups, we administered these compounds alongside pyrazinamide for four weeks.

Our findings showed that these treatments effectively protected liver tissues from damage due to oxidative stress, as measured by various biochemical and histopathological analyses.

This suggests a promising avenue for enhancing liver health during pyrazinamide therapy.
Read More
7
Vitamin B and Folate Related to Mortality
Associations of serum folate and vitamin B levels with all-cause mortality among patients with metabolic dysfunction associated steatotic liver disease: a prospective cohort study.
High relevance to liver disease research
We explored how serum folate and vitamin B levels relate to all-cause mortality among individuals with metabolic dysfunction-associated steatotic liver disease (MASLD). Utilizing data from the Third National Health and Nutrition Examination Survey, we followed nearly 3,636 MASLD subjects for over 20 years.

Our findings indicated that lower levels of these vitamins were tied to a higher risk of mortality. Specifically, individuals with serum vitamin B and folate levels above the median experienced significant reductions in mortality risk, underscoring the potential importance of these nutrients for liver health.
Read More
7
Vitamin B6 may protect liver health
The gut microbiota-produced vitamin B6 mitigates alcohol-associated liver disease by attenuating hepatic oxidative stress damage.
Moderately relevant to liver health
We investigated the connection between vitamin B6 and alcohol-associated liver disease (ALD) using a mouse model. Through a detailed analysis of the gut microbiota, we observed that disruptions significantly lowered vitamin B6 production. This reduction heightened oxidative stress and worsened liver damage. Our results indicate that maintaining vitamin B6 levels could be vital in protecting against ALD progression by influencing important metabolic processes. Despite some promising findings, the protective effects of vitamin B6 against ALD warrant further exploration before drawing definitive conclusions.
Read More

User Reviews

USERS' SCORE
Good
Based on 28 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Normalises liver function
I drink with my husband 2 course, excellent composition, well absorbed, works great. It helps to normalise liver function and improves sleep. Affects the nervous system positively, reduces anxiety and relieves stress. I noticed it improves my overall well-being. Don't fear high dosages as these are water-soluble vitamins; the body only takes what it needs, and the excess is excreted.
Read More
9.5
Normalises liver function
Perfectly absorbed, these vitamins support the nervous system and help normalise liver function. There’s no need to worry about large dosages, as they are water-soluble, meaning the body uses what it requires and excretes the rest. They also improve sleep, reduce anxiety, relieve stress, and alleviate muscle weakness.
Read More
9.5
Supports overall energy
This super complex of bioavailable B vitamins is excellent! Although urine may turn yellow, it indicates the supplement's effectiveness. As they are water-soluble, there’s no risk of overdose. Taking two daily supports the nervous system, liver, and overall energy.
9.5
Enhances well-being
These vitamins effectively normalise liver function and support the nervous system. They can be taken in large dosages without concern due to their water-soluble nature. They enhance sleep quality, reduce anxiety, relieve tension, and improve overall well-being.
9.5
Excellent for liver
This B complex is superb for liver health, and I find this brand to be truly outstanding.

Frequently Asked Questions

No FAQs are available for this product and symptom.
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